In the early stages of the COVID-19 pandemic, experts across disciplines recognized that data collection and research on COVID-19 in pregnancy were urgently needed. In April 2021, the OMNI Research Group established the COVID-19 Pregnancy Event (COPE) Network – a collaboration of 13 obstetrical hospitals in 6 of Ontario’s largest cities, which collectively handle 75% of hospital births in Ontario each year. The COPE Network includes experts in maternal-fetal-medicine, perinatal epidemiology, public health, molecular virology and infectious diseases.
Over the last 2 years we have launched a series of CIHR-funded seroprevalence, vertical transmission and surveillance investigations designed to generate rapid, rigorous evidence specific to the impacts of COVID-19 on maternal, fetal and newborn health and the role of COVID-19 vaccines for protecting mothers and their newborns. Our findings will inform strategies to optimize processes in care and patient counselling and improve health systems management of COVID-19 in pregnancy.
The purpose of this study is to find out what effects COVID-19 vaccines have on the immune systems of pregnant women/individuals and their babies. We will measure immune responses in vaccinated participants and their babies after they are born, and document vaccine-related reactions and health outcomes that may occur after vaccination.
In addition, the data from this study will be compared with data from other COVID-19 research studies. We will measure differences in the mother and baby(ies) immune responses between individuals who received a COVID-19 vaccination in pregnancy and those who had COVID-19 in pregnancy. We will also measure differences in the immune responses to COVID-19 vaccination between pregnant and non-pregnant women/individuals.
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